Amino Alcohols as Potential Antibiotic and Antifungal Leads

- Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J., McCluskey, Adam

Mechanism of transcription modulation by the transcription-repair coupling factor

- Paudel, Bishnu P., Xu, Zhi-Qiang, Ghodke, Harshad, Jergic, Slobodan, Oakley, Aaron J., Sharma, Nischal, Brown, Simon H. J., Bouwer, James C., Lewis, Peter J., Dixon, Nicholas E., van Oijen, Antoine M.

Multiple classes and isoforms of the RNA polymerase recycling motor protein HelD

- Larsen, Joachim S., Miller, Michael, Oakley, Aaron J., Dixon, Nicholas E., Lewis, Peter J.

RNA polymerases from low G+C gram-positive bacteria

- Miller, Michael, Oakley, Aaron J., Lewis, Peter J.

Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD

- Newing, Timothy P., Oakley, Aaron J., Miller, Michael, Dawson, Catherine J., Brown, Simon H. J., Bouwer, James C., Tolun, Gokhan, Lewis, Peter J.

Protein-protein interactions as antibiotic targets: a medicinal chemistry perspective

- Cossar, Peter J., Lewis, Peter J., McCluskey, Adam

First-in-class inhibitor of ribosomal RNA synthesis with antimicrobial activity against Staphylococcus aureus

- Yang, Xiao, Luo, Ming Jing, Yeung, Apple C. M., Lewis, Peter J., Chan, Paul K. S., Ip, Margaret, Ma, Cong

Identification and validation of small molecule modulators of the NusB-NusE interaction

- Cossar, Peter J., Cong, Ma, Gordon, Christopher P., Ambrus, Joseph I., Lewis, Peter J., McCluskey, Adam

In-culture cross-linking of bacterial cells reveals large-scale dynamic protein-protein interactions at the peptide level

- de Jong, Luitzen, de Koning, Edward A., Hamoen, Leendert W., de Koster, Chris G., Roseboom, Winfried, Buncherd, Hansuk, Wanner, Martin J., Dapic, Irena, Jansen, Petra J., van Maarseveen, Jan H., Corthals, Garry L., Lewis, Peter J.

Small molecule inhibitors of bacterial transcription complex formation

- Wenholz, Daniel S., Zeng, Ming, Ma, Cong, Mielczarek, Marcin, Yang, Xiao, Bhadbhade, Mohan, Black, David St. C., Lewis, Peter J., Griffith, Renate, Kumar, Naresh

Small-molecule inhibitors of the NusB-NusE protein-protein interaction with antibiotic activity

- Cossar, Peter J., Abdel-Hamid, Mohammed K., Ma, Cong, Sakoff, Jennette A., Trinh, Trieu N., Gordon, Christopher P., Lewis, Peter J., McCluskey, Adam

Activation of Xer-recombination at dif: structural basis of the FtsKγ-XerD interaction

- Keller, Andrew N., Xin, Yue, Boer, Stephanie, Reinhardt, Jonathan, Baker, Rachel, Arciszewska, Lidia K., Lewis, Peter J., Sherratt, David J., Löwe, Jan, Grainge, Ian

Bacterial transcription as a target for antibacterial drug development

- Ma, Cong, Yang, Xiao, Lewis, Peter J.

Bacterial transcription inhibitor of RNA polymerase holoenzyme formation by structure-based drug design: from in silico screening to validation

- Ma, Cong, Yang, Xiao, Lewis, Peter J.

From indole to pyrrole, furan, thiophene and pyridine: search for novel small molecule inhibitors of bacterial transcription initiation complex formation

- Thach, Oscar, Mielczarek, Marcin, Ma, Cong, Kutty, Samuel K., Yang, Xiao, Black, David StC., Griffith, Renate, Lewis, Peter J., Kumar, Naresh

Bacterial sliding clamp inhibitors that mimic the sequential binding mechanism of endogenous linear motifs.

- Yin, Zhou, Whittell, Louise R., Wang, Yao, Jergic, Slobodan, Ma, Cong, Lewis, Peter J., Dixon, Nicholas E., Beck, Jennifer L., Kelso, Michael J., Oakley, Aaron J.

Identification of inhibitors of bacterial RNA polymerase

- Yang, Xiao, Ma, Cong, Lewis, Peter J.

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.

- Ma, Cong, Mobli, Mehdi, Yang, Xiao, Keller, Andrew N., King, Glenn F., Lewis, Peter J.

Synthesis and antibacterial evaluation of novel hydrophilic ocotillol-type triterpenoid derivatives from 20(S)-protopanaxadiol

- Bi, Yi, Ma, Cong, Zhou, Zhiwen, Zhang, Tingting, Zhang, Hengyuan, Zhang, Xiaochen, Lu, Jing, Meng, Qingguo, Lewis, Peter J., Xu, Jinyi

Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation

- Mielczarek, Marcin, Thomas, Ruth V., Ma, Cong, Kandemir, Hakan, Yang, Xiao, Bhadbhade, Mohan, Black, David StC., Griffith, Renate, Lewis, Peter J., Kumar, Naresh